Covid
Parham Maroufi; Tala Pourlak
Abstract
Introduction: Determining pre-operative platelet levels and their potential correlation with intraoperative bleeding is an important area of investigation in tibia fracture surgery. Platelet parameters, including platelet count, MPV, PDW, and PCT, have shown promise as potential predictors of bleeding ...
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Introduction: Determining pre-operative platelet levels and their potential correlation with intraoperative bleeding is an important area of investigation in tibia fracture surgery. Platelet parameters, including platelet count, MPV, PDW, and PCT, have shown promise as potential predictors of bleeding tendencies during surgery. By considering these parameters and other relevant clinical factors, healthcare professionals can enhance surgical planning, optimize patient care, and improve outcomes in tibia fracture surgery.Material and Methods: Pre-operative platelet levels were determined by collecting a venous blood sample from each participant within 24 hours before surgery. The blood samples were collected using standard aseptic techniques and transferred to the hospital laboratory for analysis. Platelet counts were measured using an automated hematology analyzer, which provided accurate and reliable results. During tibia fracture surgery, the amount of bleeding was measured and recorded. The surgical team employed standard techniques for intraoperative blood loss measurement, including the use of suction devices and weighing surgical sponges.Results: The results revealed a significant positive correlation between platelet count and intraoperative bleeding (p < 0.05), indicating that higher platelet counts were associated with increased amounts of bleeding during tibia fracture surgery. However, no significant correlations were observed between MPV, PDW, PCT, and intraoperative bleeding (p > 0.05).Conclusion: this study provides evidence of a significant positive correlation between pre-operative platelet count and the amount of bleeding during tibia fracture surgery. Higher platelet counts were associated with increased amounts of bleeding, suggesting that platelet count may serve as a valuable predictor of bleeding tendencies in this surgical population.
Medicine
Parham Maroufi; Tala Pourlak
Abstract
Introduction: this study aims to investigate the levels of ficolin-2 in patients with OA and explore its relationship with age. By elucidating the potential role of ficolin-2 in OA pathophysiology and its association with age-related changes, this study may contribute to our understanding of the inflammatory ...
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Introduction: this study aims to investigate the levels of ficolin-2 in patients with OA and explore its relationship with age. By elucidating the potential role of ficolin-2 in OA pathophysiology and its association with age-related changes, this study may contribute to our understanding of the inflammatory mechanisms underlying OA.Material and Methods: Ficolin-2 levels were quantified using a dedicated human ficolin-2 enzyme-linked immunosorbent assay (ELISA) kit. The assay followed the manufacturer's instructions with duplicate measurements for each sample. Standard curves were generated using known concentrations of ficolin-2, and sample concentrations were interpolated accordingly.Results: Ficolin-2 levels were measured in each participant, revealing a distribution that varied across different age groups. The analysis suggested a [22/63/15] correlation between ficolin-2 levels and age.Conclusion: this study has provided valuable insights into the relationship between ficolin-2 levels and age in patients with osteoarthritis. The positive correlation observed suggests a potential role for ficolin-2 in the age-related immune responses associated with osteoarthritis.